A spread of more than a degree or two between points, a corner sitting outside the 80 to 85 per cent humidity band, or carbon dioxide well above the 1000 to 1500 ppm cropping band at the far end all say the same thing: the room is not distributing what the machine is making.
That is a baffle, duct, deflector or loading problem. Changing the set point to fix it only moves the whole room, and usually makes the good end wrong as well.